Ontology highlight
ABSTRACT:
SUBMITTER: Luo S
PROVIDER: S-EPMC4469202 | biostudies-literature | 2015 Jul
REPOSITORIES: biostudies-literature
Bioorganic & medicinal chemistry 20150501 13
Extract from the cultured freshwater cf. Oscillatoria sp. UIC 10045 showed antiproliferative activity against HT-29 cell line. Bioassay-guided fractionation led to the isolation of two new cyclic lipopeptides, named trichormamides C (1) and D (2). The planar structures were determined by combined analyses of HRESIMS, Q-TOF ESIMS/MS, and 1D and 2D NMR spectra. The absolute configurations of the amino acid residues were assigned by advanced Marfey's analysis after partial and complete acid hydroly ...[more]