Ontology highlight
ABSTRACT:
SUBMITTER: Lyu S
PROVIDER: S-EPMC4476480 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Lyu Shixu S Ye Lechi L Wang Ouchen O Huang Guanli G Yang Fan F Liu Yehuan Y Dong Siyang S
OncoTargets and therapy 20150616
IL-27, a new member of the IL-12 family, has been found to have antitumor effects in colorectal cancer (CRC); therefore, polymorphisms of this protein may modulate CRC carcinogenesis. So, we studied the association of single nucleotide polymorphisms of the IL-27 gene with the risk of CRC occurrence using a case-control using 600 CRC patients and matched healthy controls. The IL-27 rs153109 polymorphism was analyzed with polymerase chain reaction-restriction fragment length polymorphism and DNA s ...[more]