Ontology highlight
ABSTRACT:
SUBMITTER: Springelkamp H
PROVIDER: S-EPMC4480365 | biostudies-literature | 2015 Mar
REPOSITORIES: biostudies-literature
Springelkamp Henriët H Mishra Aniket A Hysi Pirro G PG Gharahkhani Puya P Höhn René R Khor Chiea-Chuen CC Cooke Bailey Jessica N JN Luo Xiaoyan X Ramdas Wishal D WD Vithana Eranga E Koh Victor V Yazar Seyhan S Xu Liang L Forward Hannah H Kearns Lisa S LS Amin Najaf N Iglesias Adriana I AI Sim Kar-Seng KS van Leeuwen Elisabeth M EM Demirkan Ayse A van der Lee Sven S Loon Seng-Chee SC Rivadeneira Fernando F Nag Abhishek A Sanfilippo Paul G PG Schillert Arne A de Jong Paulus T V M PT Oostra Ben A BA Uitterlinden André G AG Hofman Albert A Zhou Tiger T Burdon Kathryn P KP Spector Timothy D TD Lackner Karl J KJ Saw Seang-Mei SM Vingerling Johannes R JR Teo Yik-Ying YY Pasquale Louis R LR Wolfs Roger C W RC Lemij Hans G HG Tai E-Shyong ES Jonas Jost B JB Cheng Ching-Yu CY Aung Tin T Jansonius Nomdo M NM Klaver Caroline C W CC Craig Jamie E JE Young Terri L TL Haines Jonathan L JL MacGregor Stuart S Mackey David A DA Pfeiffer Norbert N Wong Tien-Yin TY Wiggs Janey L JL Hewitt Alex W AW van Duijn Cornelia M CM Hammond Christopher J CJ
Genetic epidemiology 20150128 3
Primary open-angle glaucoma is the most common optic neuropathy and an important cause of irreversible blindness worldwide. The optic nerve head or optic disc is divided in two parts: a central cup (without nerve fibers) surrounded by the neuroretinal rim (containing axons of the retinal ganglion cells). The International Glaucoma Genetics Consortium conducted a meta-analysis of genome-wide association studies consisting of 17,248 individuals of European ancestry and 6,841 individuals of Asian a ...[more]