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Hemagglutinin Receptor Binding of a Human Isolate of Influenza A(H10N8) Virus.


ABSTRACT: Three cases of influenza A(H10N8) virus infection in humans have been reported; 2 of these infected persons died. Characterization of the receptor binding pattern of H10 hemagglutinin from avian and human isolates showed that both interact weakly with human-like receptors and maintain strong affinity for avian-like receptors.

SUBMITTER: Ramos I 

PROVIDER: S-EPMC4480385 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature

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Hemagglutinin Receptor Binding of a Human Isolate of Influenza A(H10N8) Virus.

Ramos Irene I   Mansour Mena M   Wohlbold Teddy J TJ   Ermler Megan E ME   Hirsh Ariana A   Runstadler Jonathan A JA   Fernandez-Sesma Ana A   Krammer Florian F  

Emerging infectious diseases 20150701 7


Three cases of influenza A(H10N8) virus infection in humans have been reported; 2 of these infected persons died. Characterization of the receptor binding pattern of H10 hemagglutinin from avian and human isolates showed that both interact weakly with human-like receptors and maintain strong affinity for avian-like receptors. ...[more]

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