Ontology highlight
ABSTRACT:
SUBMITTER: Caceres M
PROVIDER: S-EPMC4482413 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Cáceres Mónica M Ortiz Liliana L Recabarren Tatiana T Romero Anibal A Colombo Alicia A Leiva-Salcedo Elías E Varela Diego D Rivas José J Silva Ian I Morales Diego D Campusano Camilo C Almarza Oscar O Simon Felipe F Toledo Hector H Park Kang-Sik KS Trimmer James S JS Cerda Oscar O
PloS one 20150625 6
Cellular migration and contractility are fundamental processes that are regulated by a variety of concerted mechanisms such as cytoskeleton rearrangements, focal adhesion turnover, and Ca2+ oscillations. TRPM4 is a Ca2+-activated non-selective cationic channel (Ca2+-NSCC) that conducts monovalent but not divalent cations. Here, we used a mass spectrometry-based proteomics approach to identify putative TRPM4-associated proteins. Interestingly, the largest group of these proteins has actin cytoske ...[more]