Ontology highlight
ABSTRACT:
SUBMITTER: Liang EI
PROVIDER: S-EPMC5399776 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Liang Elena I EI Mah Emma J EJ Yee Albert F AF Digman Michelle A MA Digman Michelle A MA
Integrative biology : quantitative biosciences from nano to macro 20170201 2
Selective cell adhesion is desirable to control cell growth and migration on biomedical implants. Mesenchymal cell migration is regulated through focal adhesions (FAs) and can be modulated by their microenvironment, including changes in surface topography. We use the Number and Molecular Brightness (N&B) imaging analysis to provide a unique perspective on FA assembly and disassembly. This imaging analysis generates a map of real-time fluctuations of protein monomers, dimers, and higher order agg ...[more]