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Novel oral taxane therapies: recent Phase I results.


ABSTRACT: The oral taxanes are analogues of existing taxanes with a possible broad range of antitumor activity. They also have the potential advantages of ease of administration, better efficacy and lesser toxicity than currently available taxanes. These drugs have been used in several Phase I clinical trials, the methodology and results of which will be reviewed here.

SUBMITTER: Flores JP 

PROVIDER: S-EPMC4489850 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature

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Novel oral taxane therapies: recent Phase I results.

Flores John Paul JP   Saif M Wasif MW  

Clinical investigation 20130101 4


The oral taxanes are analogues of existing taxanes with a possible broad range of antitumor activity. They also have the potential advantages of ease of administration, better efficacy and lesser toxicity than currently available taxanes. These drugs have been used in several Phase I clinical trials, the methodology and results of which will be reviewed here. ...[more]

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