Ontology highlight
ABSTRACT:
SUBMITTER: Adhikari K
PROVIDER: S-EPMC4491814 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
Nature communications 20150624
Here we report a genome-wide association study for non-pathological pinna morphology in over 5,000 Latin Americans. We find genome-wide significant association at seven genomic regions affecting: lobe size and attachment, folding of antihelix, helix rolling, ear protrusion and antitragus size (linear regression P values 2 × 10(-8) to 3 × 10(-14)). Four traits are associated with a functional variant in the Ectodysplasin A receptor (EDAR) gene, a key regulator of embryonic skin appendage developm ...[more]