Ontology highlight
ABSTRACT:
SUBMITTER: Earley ZM
PROVIDER: S-EPMC4496078 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Earley Zachary M ZM Akhtar Suhail S Green Stefan J SJ Naqib Ankur A Khan Omair O Cannon Abigail R AR Hammer Adam M AM Morris Niya L NL Li Xiaoling X Eberhardt Joshua M JM Gamelli Richard L RL Kennedy Richard H RH Choudhry Mashkoor A MA
PloS one 20150708 7
Sepsis remains one of the leading causes of death in burn patients who survive the initial insult of injury. Disruption of the intestinal epithelial barrier has been shown after burn injury; this can lead to the translocation of bacteria or their products (e.g., endotoxin) from the intestinal lumen to the circulation, thereby increasing the risk for sepsis in immunocompromised individuals. Since the maintenance of the epithelial barrier is largely dependent on the intestinal microbiota, we exami ...[more]