Ontology highlight
ABSTRACT:
SUBMITTER: Simonicova L
PROVIDER: S-EPMC4496324 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Simonicova Lucia L Dudekova Henrieta H Ferenc Jaroslav J Prochazkova Katarina K Nebohacova Martina M Dusinsky Roman R Nosek Jozef J Tomaska Lubomir L
Current genetics 20150108 4
The experimental evidence from the last decade made telomerase a prominent member of a family of moonlighting proteins performing different functions at various cellular loci. However, the study of extratelomeric functions of the catalytic subunit of mammalian telomerase (TERT) is often complicated by the fact that it is sometimes difficult to distinguish them from its role(s) at the chromosomal ends. Here, we present an experimental model for studying the extranuclear function(s) of mammalian t ...[more]