Ontology highlight
ABSTRACT:
SUBMITTER: Rydzik AM
PROVIDER: S-EPMC4497603 | biostudies-literature | 2014 Oct
REPOSITORIES: biostudies-literature
Rydzik Anna M AM Leung Ivanhoe K H IK Kochan Grazyna T GT McDonough Michael A MA Claridge Timothy D W TD Schofield Christopher J CJ
Angewandte Chemie (International ed. in English) 20140827 41
γ-Butyrobetaine hydroxylase (BBOX) is a 2-oxoglutarate dependent oxygenase that catalyzes the final hydroxylation step in the biosynthesis of carnitine. BBOX was shown to catalyze the oxidative desymmetrization of achiral N,N-dialkyl piperidine-4-carboxylates to give products with two or three stereogenic centers. ...[more]