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Advances in the management of gastrointestinal cancers--an upcoming role of immune checkpoint blockade.

ABSTRACT: Gastrointestinal cancers are a group of highly aggressive malignancies, and novel therapeutic strategies with higher clinical efficacy are being actively sought. 'Immunotherapy' is now emerging as one such promising strategy for the treatment of these tumors. This article briefly reviews the recent advances that utilize targeting of immune checkpoint pathways, in the management of gastrointestinal malignancies.

SUBMITTER: Goel G

PROVIDER: S-EPMC4502562 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature

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Advances in the management of gastrointestinal cancers--an upcoming role of immune checkpoint blockade.

Goel Gaurav G Sun Weijing W

Journal of hematology & oncology 20150716

Gastrointestinal cancers are a group of highly aggressive malignancies, and novel therapeutic strategies with higher clinical efficacy are being actively sought. 'Immunotherapy' is now emerging as one such promising strategy for the treatment of these tumors. This article briefly reviews the recent advances that utilize targeting of immune checkpoint pathways, in the management of gastrointestinal malignancies. ...[more]

PMID: 26174086

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