Ontology highlight
ABSTRACT:
SUBMITTER: Reuter LM
PROVIDER: S-EPMC4526739 | biostudies-literature | 2015 Jul
REPOSITORIES: biostudies-literature
Reuter L Maximilian LM Meinel Dominik M DM Sträßer Katja K
Genes & development 20150701 14
RNA polymerase III (RNAPIII) synthesizes most small RNAs, the most prominent being tRNAs. Although the basic mechanism of RNAPIII transcription is well understood, recent evidence suggests that additional proteins play a role in RNAPIII transcription. Here, we discovered by a genome-wide approach that Nab2, a poly(A)-binding protein important for correct poly(A) tail length and nuclear mRNA export, is present at all RNAPIII transcribed genes. The occupancy of Nab2 at RNAPIII transcribed genes is ...[more]