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Photo-click living strategy for controlled, reversible exchange of biochemical ligands.

ABSTRACT: A novel addition-fragmentation-chain transfer capable allyl sulfide functionalized PEG hydrogel is reported to allow controlled, reversible exchange of biochemical ligands. The exchange of biochemical ligands is achieved without permanent consumption of reactive functionalities. Demonstrated is the ability to exchange biochemical ligands multiple times using cytocompatible 720 nm two-photon light.

SUBMITTER: Gandavarapu NR 

PROVIDER: S-EPMC4528616 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature

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Photo-click living strategy for controlled, reversible exchange of biochemical ligands.

Gandavarapu Navakanth R NR   Azagarsamy Malar A MA   Anseth Kristi S KS  

Advanced materials (Deerfield Beach, Fla.) 20140212 16

A novel addition-fragmentation-chain transfer capable allyl sulfide functionalized PEG hydrogel is reported to allow controlled, reversible exchange of biochemical ligands. The exchange of biochemical ligands is achieved without permanent consumption of reactive functionalities. Demonstrated is the ability to exchange biochemical ligands multiple times using cytocompatible 720 nm two-photon light. ...[more]

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