Ontology highlight
ABSTRACT:
SUBMITTER: Valsangkar VA
PROVIDER: S-EPMC6687541 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Valsangkar Vibhav A VA Chandrasekaran Arun Richard AR Zhuo Lifeng L Mao Song S Lee Goh Woon GW Kizer Megan M Wang Xing X Halvorsen Ken K Sheng Jia J
Chemical communications (Cambridge, England) 20190729 65
We functionalize nucleic acid nanostructures with click chemistry (for attachment of cargos) and a photocleavable linker (for release). We demonstrate cargo attachment using a fluorescein dye and release using UV trigger from an RNA three-way junction, a DNA star motif and a DNA tetrahedron. Such multifunctional nucleic acid nanostructures have potential in targeted drug delivery. ...[more]