Ontology highlight
ABSTRACT:
SUBMITTER: Galhardo M
PROVIDER: S-EPMC4536030 | biostudies-literature | 2014 Dec
REPOSITORIES: biostudies-literature
Galhardo Mafalda M Sinkkonen Lasse L Berninger Philipp P Lin Jake J Sauter Thomas T Heinäniemi Merja M
Genomics data 20140806
Transcription factors (TFs) represent key factors to establish a cellular phenotype. It is known that several TFs could play a role in disease, yet less is known so far how their targets overlap. We focused here on identifying the most highly induced TFs and their putative targets during human adipogenesis. Applying chromatin immunoprecipitation coupled with deep sequencing (ChIP-Seq) in the human SGBS pre-adipocyte cell line, we identified genes with binding sites in their vicinity for the thre ...[more]