Cross-species ChIP-seq studies provide insights into regulatory strategies of PPAR? in adipocytes.
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ABSTRACT:
SUBMITTER: Schmidt SF
PROVIDER: S-EPMC3679271 | biostudies-literature | 2012 Jan-Feb
REPOSITORIES: biostudies-literature
Publications
Cross-species ChIP-seq studies provide insights into regulatory strategies of PPARγ in adipocytes.
Schmidt Søren F SF Jørgensen Mette M Sandelin Albin A Mandrup Susanne S
Transcription 20120101 1
Three recent studies have investigated interspecies retention of binding sites of peroxisome proliferator-activated receptor γ (PPARγ), the master regulator of adipocyte differention, between mouse and human adipocytes. Here we discuss the major findings and demonstrate that retention of binding events is highly context-dependent. ...[more]
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