Ontology highlight
ABSTRACT:
SUBMITTER: Funato N
PROVIDER: S-EPMC4549757 | biostudies-literature | 2015 Aug
REPOSITORIES: biostudies-literature
Funato Noriko N Nakamura Masataka M Yanagisawa Hiromi H
World journal of biological chemistry 20150801 3
Cleft palate, including complete or incomplete cleft palates, soft palate clefts, and submucosal cleft palates, is the most frequent congenital craniofacial anomaly in humans. Multifactorial conditions, including genetic and environmental factors, induce the formation of cleft palates. The process of palatogenesis is temporospatially regulated by transcription factors, growth factors, extracellular matrix proteins, and membranous molecules; a single ablation of these molecules can result in a cl ...[more]