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Bundle-forming ?-helical peptide-dendron hybrid.


ABSTRACT: Peptides and dendrons are enticing building blocks from which to construct hybrid macromolecules because each can be prepared as monodisperse and sequence defined materials. Folding and assembly properties designed into the amino acid sequence of a peptide-dendron hybrid manifest in the formation of a dendronized bundle of ?-helices.

SUBMITTER: Marine JE 

PROVIDER: S-EPMC4567505 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature

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Bundle-forming α-helical peptide-dendron hybrid.

Marine Jeannette E JE   Song Shuang S   Liang Xiaoli X   Watson Matthew D MD   Rudick Jonathan G JG  

Chemical communications (Cambridge, England) 20150813 76


Peptides and dendrons are enticing building blocks from which to construct hybrid macromolecules because each can be prepared as monodisperse and sequence defined materials. Folding and assembly properties designed into the amino acid sequence of a peptide-dendron hybrid manifest in the formation of a dendronized bundle of α-helices. ...[more]

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