RNAi-mediated RPL34 knockdown suppresses the growth of human gastric cancer cells.
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ABSTRACT:
SUBMITTER: Liu H
PROVIDER: S-EPMC4583519 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Publications
RNAi-mediated RPL34 knockdown suppresses the growth of human gastric cancer cells.
Liu Hui H Liang Shaohua S Yang Xi X Ji Zhaoning Z Zhao Wenying W Ye Xiaobing X Rui Jing J
Oncology reports 20150821 5
An increasing body of evidence suggests that ribosomal proteins may have ribosome-independent functions and may be involved in various physiological and pathological processes. To examine the role of ribosomal protein L34 (RPL34) in cancer transformation, we assessed its expression in gastric cancer cell lines and found it highly expressed. We further used lentivirus-mediated small interfering RNAs (siRNAs) to knockdown RPL34 expression in the human gastric cancer cell line SGC-7901. RNA interfe ...[more]
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