Ontology highlight
ABSTRACT:
SUBMITTER: Shrivastava N
PROVIDER: S-EPMC4592873 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Shrivastava Nidhi N Prokop Zbynek Z Kumar Ashwani A
Applied and environmental microbiology 20150821 21
LinA is the first enzyme of the microbial degradation pathway of a chlorinated insecticide, hexachlorocyclohexane (HCH), and mediates the dehydrochlorination of α-, γ-, and δ-HCH. Its two variants, LinA type 1 and LinA type 2, which differ at 10 out of 156 amino acid residues, have been described. Their activities for the metabolism of different HCH isomers differ considerably but overall are high for γ-HCH, moderate for α-HCH, low for δ-HCH, and lacking for β-HCH. Here, we describe the characte ...[more]