The 82-plex plasma protein signature that predicts increasing inflammation.
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ABSTRACT:
SUBMITTER: Tepel M
PROVIDER: S-EPMC4597208 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Publications
The 82-plex plasma protein signature that predicts increasing inflammation.
Tepel Martin M Beck Hans C HC Tan Qihua Q Borst Christoffer C Rasmussen Lars M LM
Scientific reports 20151008
The objective of the study was to define the specific plasma protein signature that predicts the increase of the inflammation marker C-reactive protein from index day to next-day using proteome analysis and novel bioinformatics tools. We performed a prospective study of 91 incident kidney transplant recipients and quantified 359 plasma proteins simultaneously using nano-Liquid-Chromatography-Tandem Mass-Spectrometry in individual samples and plasma C-reactive protein on the index day and the nex ...[more]
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