Ontology highlight
ABSTRACT:
SUBMITTER: Tsai LC
PROVIDER: S-EPMC4601590 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Tsai Li Chu LC Amiraslanov Imamaddin I Chen Hung Ren HR Chen Yun Wen YW Lee Hsiao Lin HL Liang Po Huang PH Liaw Yen Chywan YC
Acta crystallographica. Section F, Structural biology communications 20150923 Pt 10
Exoglucanase/cellobiohydrolase (EC 3.2.1.176) hydrolyzes a β-1,4-glycosidic bond from the reducing end of cellulose and releases cellobiose as the major product. Three complex crystal structures of the glycosyl hydrolase 48 (GH48) cellobiohydrolase S (ExgS) from Clostridium cellulovorans with cellobiose, cellotetraose and triethylene glycol molecules were solved. The product cellobiose occupies subsites +1 and +2 in the open active-site cleft of the enzyme-cellotetraose complex structure, indica ...[more]