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PERSONALITY AND DEPRESSIVE SYMPTOMS: INDIVIDUAL PARTICIPANT META-ANALYSIS OF 10 COHORT STUDIES.


ABSTRACT: BACKGROUND:Personality is suggested to be a major risk factor for depression but large-scale individual participant meta-analyses on this topic are lacking. METHOD:Data from 10 prospective community cohort studies with 117,899 participants (mean age 49.0 years; 54.7% women) were pooled for individual participant meta-analysis to determine the association between personality traits of the five-factor model and risk of depressive symptoms. RESULTS:In cross-sectional analysis, low extraversion (pooled standardized regression coefficient (B) = -.08; 95% confidence interval = -0.11, -0.04), high neuroticism (B = .39; 0.32, 0.45), and low conscientiousness (B = -.09; -0.10, -0.06) were associated with depressive symptoms. Similar associations were observed in longitudinal analyses adjusted for baseline depressive symptoms (n = 56,735; mean follow-up of 5.0 years): low extraversion (B = -.03; -0.05, -0.01), high neuroticism (B = .12; 0.10, 0.13), and low conscientiousness (B = -.04; -0.06, -0.02) were associated with an increased risk of depressive symptoms at follow-up. In turn, depressive symptoms were associated with personality change in extraversion (B = -.07; 95% CI = -0.12, -0.02), neuroticism (B = .23; 0.09, 0.36), agreeableness (B = -.09; -0.15, -0.04), conscientiousness (B = -.14; -0.21, -0.07), and openness to experience (B = -.04; -0.08, 0.00). CONCLUSIONS:Personality traits are prospectively associated with the development of depressive symptoms. Depressive symptoms, in turn, are associated with changes in personality that may be temporary or persistent.

SUBMITTER: Hakulinen C 

PROVIDER: S-EPMC4605994 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature

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PERSONALITY AND DEPRESSIVE SYMPTOMS: INDIVIDUAL PARTICIPANT META-ANALYSIS OF 10 COHORT STUDIES.

Hakulinen Christian C   Elovainio Marko M   Pulkki-Råback Laura L   Virtanen Marianna M   Kivimäki Mika M   Jokela Markus M  

Depression and anxiety 20150526 7


<h4>Background</h4>Personality is suggested to be a major risk factor for depression but large-scale individual participant meta-analyses on this topic are lacking.<h4>Method</h4>Data from 10 prospective community cohort studies with 117,899 participants (mean age 49.0 years; 54.7% women) were pooled for individual participant meta-analysis to determine the association between personality traits of the five-factor model and risk of depressive symptoms.<h4>Results</h4>In cross-sectional analysis,  ...[more]

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