Ontology highlight
ABSTRACT:
SUBMITTER: Wilken JA
PROVIDER: S-EPMC4620931 | biostudies-literature | 2012 Mar
REPOSITORIES: biostudies-literature
Wilken Jason A JA Badri Tayf T Cross Sarah S Raji Rhoda R Santin Alessandro D AD Schwartz Peter P Branscum Adam J AJ Baron Andre T AT Sakhitab Adam I AI Maihle Nita J NJ
Future medicinal chemistry 20120301 4
Despite decades of research and evolving treatment modalities, survival among patients with epithelial ovarian cancer has improved only incrementally. During this same period, the development of biologically targeted therapeutics has improved survival for patients with diverse malignancies. Many of these new drugs target the human epidermal growth factor receptor (EGFR/HER/ErbB) family of tyrosine kinases, which play a major role in the etiology and progression of many carcinomas, including epit ...[more]