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Thermoresponsive release of viable microfiltrated Circulating Tumor Cells (CTCs) for precision medicine applications.

ABSTRACT: Stimulus responsive release of Circulating Tumor Cells (CTCs), with high recovery rates from their capture platform, is highly desirable for off-chip analyses. Here, we present a temperature responsive polymer coating method to achieve both release as well as culture of viable CTCs captured from patient blood samples.

SUBMITTER: Ao Z

PROVIDER: S-EPMC4624465 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature

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Thermoresponsive release of viable microfiltrated Circulating Tumor Cells (CTCs) for precision medicine applications.

Ao Zheng Z Parasido Erika E Rawal Siddarth S Williams Anthony A Schlegel Richard R Liu Stephen S Albanese Chris C Cote Richard J RJ Agarwal Ashutosh A Datar Ram H RH

Lab on a chip 20151101 22

Stimulus responsive release of Circulating Tumor Cells (CTCs), with high recovery rates from their capture platform, is highly desirable for off-chip analyses. Here, we present a temperature responsive polymer coating method to achieve both release as well as culture of viable CTCs captured from patient blood samples. ...[more]

PMID: 26426331

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