Ontology highlight
ABSTRACT:
SUBMITTER: Leslie S
PROVIDER: S-EPMC4632200 | biostudies-literature | 2015 Mar
REPOSITORIES: biostudies-literature
Leslie Stephen S Winney Bruce B Hellenthal Garrett G Davison Dan D Boumertit Abdelhamid A Day Tammy T Hutnik Katarzyna K Royrvik Ellen C EC Cunliffe Barry B Lawson Daniel J DJ Falush Daniel D Freeman Colin C Pirinen Matti M Myers Simon S Robinson Mark M Donnelly Peter P Bodmer Walter W
Nature 20150301 7543
Fine-scale genetic variation between human populations is interesting as a signature of historical demographic events and because of its potential for confounding disease studies. We use haplotype-based statistical methods to analyse genome-wide single nucleotide polymorphism (SNP) data from a carefully chosen geographically diverse sample of 2,039 individuals from the United Kingdom. This reveals a rich and detailed pattern of genetic differentiation with remarkable concordance between genetic ...[more]