Ontology highlight
ABSTRACT:
SUBMITTER: Della Chiesa M
PROVIDER: S-EPMC4638145 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Della Chiesa Mariella M Sivori Simona S Carlomagno Simona S Moretta Lorenzo L Moretta Alessandro A
Frontiers in immunology 20151109
Natural killer (NK) cells are important players in the immune defense against viral infections. The contribution of activating killer immunoglobulin-like receptors (KIRs) and CD94/NKG2C in regulating anti-viral responses has recently emerged. Thus, in the hematopoietic stem cell transplantation setting, the presence of donor activating KIRs (aKIRs) may protect against viral infections, while in HIV-infected individuals, KIR3DS1, in combination with HLA-Bw4-I80, results in reduction of viral prog ...[more]