Ontology highlight
ABSTRACT:
SUBMITTER: Lee E
PROVIDER: S-EPMC4648999 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Lee Eunjung E Stram Daniel O DO Ek Weronica E WE Onstad Lynn E LE MacGregor Stuart S Gharahkhani Puya P Ye Weimin W Lagergren Jesper J Shaheen Nicholas J NJ Murray Liam J LJ Hardie Laura J LJ Gammon Marilie D MD Chow Wong-Ho WH Risch Harvey A HA Corley Douglas A DA Levine David M DM Whiteman David C DC Bernstein Leslie L Bird Nigel C NC Vaughan Thomas L TL Wu Anna H AH
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20150912 11
<h4>Background</h4>Several cancer-associated loci identified from genome-wide association studies (GWAS) have been associated with risks of multiple cancer sites, suggesting pleiotropic effects. We investigated whether GWAS-identified risk variants for other common cancers are associated with risk of esophageal adenocarcinoma (EA) or its precursor, Barrett's esophagus.<h4>Methods</h4>We examined the associations between risks of EA and Barrett's esophagus and 387 SNPs that have been associated w ...[more]