Ontology highlight
ABSTRACT:
SUBMITTER: Spagnolo B
PROVIDER: S-EPMC4650598 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Spagnolo Barbara B Brunetti Virgilio V Leménager Godefroy G De Luca Elisa E Sileo Leonardo L Pellegrino Teresa T Paolo Pompa Pier P De Vittorio Massimo M Pisanello Ferruccio F
Scientific reports 20150527
Cancer cell motility is one of the major events involved in metastatic process. Tumor cells that disseminate from a primary tumor can migrate into the vascular system and, being carried by the bloodstream, transmigrate across the endothelium, giving rise to a new tumor site. However, during the invasive process, tumor cells must pass through the extracellular matrix, whose structural and mechanical properties define the parameters of the migration process. Here, we propose 3D-complex cage-like m ...[more]