Ontology highlight
ABSTRACT:
SUBMITTER: Singh PP
PROVIDER: S-EPMC4650981 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Singh Preet Paul PP Sharma Piyush K PK Krishnan Gayathri G Lockhart A Craig AC
Gastroenterology report 20151027 4
Colorectal cancer (CRC) remains one of the major causes of death worldwide, despite steady improvement in early detection and overall survival over the past decade. Current treatment paradigms, with chemotherapy and biologics, appear to have reached their maximum benefit. Immunotherapy, especially with checkpoint inhibitors, has shown considerable clinical benefit in various cancers, including mismatch-repair-deficient CRC. This has led to the planning and initiation of several clinical trials e ...[more]