A generalized slab-wise framework for parallel transmit multiband RF pulse design.

ABSTRACT: We propose a new slab-wise framework to design parallel transmit multiband pulses for volumetric simultaneous multislice imaging with a large field of view along the slice direction (FOVs).The slab-wise framework divides FOVs into a few contiguous slabs and optimizes pulses for each slab. Effects of relevant design parameters including slab number and transmit B1 (B1+) mapping slice placement were investigated for human brain imaging by designing pulses with global or local SAR control based on electromagnetic simulations of a 7T head RF array. Pulse design using in vivo B1+ maps was demonstrated and evaluated with Bloch simulations.RF performance with respect to SAR reduction or B1+ homogenization across the entire human brain improved with increasing slabs; however, this improvement was nonlinear and leveled off at ?12 slabs when the slab thickness reduced to ?12 mm. The impact of using different slice placements for B1+ mapping was small.Compared with slice-wise approaches where each of the many imaging slices requires both B1+ mapping and pulse optimization, the proposed slab-wise design framework attained comparable RF performance while drastically reducing the number of required pulses; therefore, it can be used to increase time efficiency for B1+ mapping, pulse calculation, and sequence preparation.

SUBMITTER: Wu X 

PROVIDER: S-EPMC4654723 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature