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IMPULSE: A scalable algorithm for design of minimum specific absorption rate parallel transmit RF pulses.

ABSTRACT: PURPOSE:Managing local specific absorption rate (SAR) in parallel transmission requires ensuring that the peak SAR over a large number of voxels (> 105 ) is below the regulatory limit. The safety risk to the patient depends on cumulative (not instantaneous) SAR thus making a joint design of all RF pulses in a sequence desirable. We propose the Iterative Minimization Procedure with Uncompressed Local SAR Estimate (IMPULSE), an efficient optimization formulation and algorithm that can handle uncompressed SAR matrices and optimize pulses for all slices jointly within a practical time frame. THEORY AND METHODS:IMPULSE optimizes parallel transmit pulses for small-tip-angle slice selective excitation to minimize a single cost function incorporating multiple quantities (local SAR, global SAR, and per-channel power) averaged over the entire multislice scan subject to a strict constraint on excitation accuracy. Pulses for an 8-channel 7T head coil were designed with IMPULSE and compared with pulses designed using generic optimization algorithms and VOPs to assess the computation time and SAR performance benefits. RESULTS:IMPULSE achieves lower SAR and shorter computation time compared with a VOP approach. Compared with the generic sequential quadratic programming algorithm, computation time is reduced by a factor of 5-6 by using IMPULSE. Using as many as 6 million local SAR terms, up to 120 slices can be designed jointly with IMPULSE within 45 s. CONCLUSIONS:IMPULSE can handle significantly larger number of SAR matrices and slices than conventional optimization algorithms, enabling the use of uncompressed or partially compressed SAR matrices to design pulses for a multislice scan in a practical time frame.

SUBMITTER: Pendse M

PROVIDER: S-EPMC6372346 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature

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IMPULSE: A scalable algorithm for design of minimum specific absorption rate parallel transmit RF pulses.

Pendse Mihir M Stara Riccardo R Mehdi Khalighi Mohammad M Rutt Brian B

Magnetic resonance in medicine 20181113 4

<h4>Purpose</h4>Managing local specific absorption rate (SAR) in parallel transmission requires ensuring that the peak SAR over a large number of voxels (> 105 ) is below the regulatory limit. The safety risk to the patient depends on cumulative (not instantaneous) SAR thus making a joint design of all RF pulses in a sequence desirable. We propose the Iterative Minimization Procedure with Uncompressed Local SAR Estimate (IMPULSE), an efficient optimization formulation and algorithm that can hand ...[more]

PMID: 30426583

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Project description:Transmit Array Spatial Encoding (TRASE) is a promising new MR encoding method that uses transmit RF (B1(+)) phase gradients over the field-of-view to perform Fourier spatial encoding. Acquisitions use a spin echo train in which the transmit coil phase ramp is modulated to jump from one k-space point to the next. This work extends the capability of TRASE by using swept radiofrequency (RF) pulses and a quadratic phase removal method to enable TRASE where it is arguably most needed: portable imaging systems with inhomogeneous B0 fields. The approach is particularly well-suited for portable MR scanners where (a) inhomogeneous B0 fields are a byproduct of lightweight magnet design, (b) heavy, high power-consumption gradient coil systems are a limitation to siting the system in non-conventional locations and (c) synergy with the use of spin echo trains is required to overcome intra-voxel dephasing (short T2(?)) in the inhomogeneous field. TRASE does not use a modulation of the B0 field to encode, but it does suffer from secondary effects of the inhomogeneous field. Severe artifacts arise in TRASE images due to off-resonance effects when the RF pulse does not cover the full bandwidth of spin resonances in the imaging FOV. Thus, for highly inhomogeneous B0 fields, the peak RF power needed for high-bandwidth refocusing hard pulses becomes very expensive, in addition to requiring RF coils that can withstand thousands of volts. In this work, we use swept WURST RF pulse echo trains to achieve TRASE imaging in a highly inhomogeneous magnetic field (?B0/B0?0.33% over the sample). By accurately exciting and refocusing the full bandwidth of spins, the WURST pulses eliminate artifacts caused by the limited bandwidth of the hard pulses used in previous realizations of TRASE imaging. We introduce a correction scheme to remove the unwanted quadratic phase modulation caused by the swept pulses. Also, a phase alternation scheme is employed to mitigate artifacts caused by mixture of the even and odd-echo coherence pathways due to defects in the refocusing pulse. In this paper, we describe this needed methodology and demonstrate the ability of TRASE to Fourier encode in an inhomogeneous field (?B0/B0?1% over the full FOV).

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IMPULSE: A scalable algorithm for design of minimum specific absorption rate parallel transmit RF pulses.

Publications

IMPULSE: A scalable algorithm for design of minimum specific absorption rate parallel transmit RF pulses.

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