Ontology highlight
ABSTRACT:
SUBMITTER: Ruiz P
PROVIDER: S-EPMC4655502 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Ruiz Paulina P Maldonado Paula P Hidalgo Yessia Y Sauma Daniela D Rosemblatt Mario M Bono Maria Rosa MR
Frontiers in immunology 20151123
The induction of donor-specific transplant tolerance is one of the main goals of modern immunology. Establishment of a mixed chimerism state in the transplant recipient has proven to be a suitable strategy for the induction of long-term allograft tolerance; however, current experimental recipient preconditioning protocols have many side effects, and are not feasible for use in future therapies. In order to improve the current mixed chimerism induction protocols, we developed a non-myeloablative ...[more]