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Determining the Presence of Superantigens in Coagulase Negative Staphylococci from Humans.


ABSTRACT: Superantigens (SAgs) are important virulence factors in S. aureus. Recent studies identified their presence in animal coagulase-negative staphylococci (CNS). The emergence of human-associated SAg+ CNS would mark a prodigious shift in virulence capabilities. We examined CNS isolates from healthy human nares and diseased individuals, and determined that no known SAgs were present.

SUBMITTER: Stach CS 

PROVIDER: S-EPMC4658126 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature

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Determining the Presence of Superantigens in Coagulase Negative Staphylococci from Humans.

Stach Christopher S CS   Vu Bao G BG   Schlievert Patrick M PM  

PloS one 20151123 11


Superantigens (SAgs) are important virulence factors in S. aureus. Recent studies identified their presence in animal coagulase-negative staphylococci (CNS). The emergence of human-associated SAg+ CNS would mark a prodigious shift in virulence capabilities. We examined CNS isolates from healthy human nares and diseased individuals, and determined that no known SAgs were present. ...[more]

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