Ontology highlight
ABSTRACT:
SUBMITTER: Shinoda K
PROVIDER: S-EPMC4670581 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Shinoda Kosaku K Ohyama Kana K Hasegawa Yutaka Y Chang Hsin-Yi HY Ogura Mayu M Sato Ayaka A Hong Haemin H Hosono Takashi T Sharp Louis Z LZ Scheel David W DW Graham Mark M Ishihama Yasushi Y Kajimura Shingo S
Cell metabolism 20151108 6
Catecholamines promote lipolysis both in brown and white adipocytes, whereas the same stimuli preferentially activate thermogenesis in brown adipocytes. Molecular mechanisms for the adipose-selective activation of thermogenesis remain poorly understood. Here, we employed quantitative phosphoproteomics to map global and temporal phosphorylation profiles in brown, beige, and white adipocytes under β3-adrenenoceptor activation and identified kinases responsible for the adipose-selective phosphoryla ...[more]