Ontology highlight
ABSTRACT:
SUBMITTER: Schaal K
PROVIDER: S-EPMC4673181 | biostudies-literature | 2015 Sep
REPOSITORIES: biostudies-literature
Schaal Kathrin K Hirschfeld Marc M Bronsert Peter P Füllgraf Hannah H Jäger Markus M Herde Bettina B Nöthling Claudia C Mayer Sebastian S Erbes Thalia T Stickeler Elmar E
Oncotarget 20150901 26
Synuclein gamma (SNCG) is under consideration as a potential biomarker in cancer biology. Up to date four different SNCG variants are described. Due to growing evidence suggesting correlations between aberrant alternative splicing processes and cancer progression, we investigated the effects of peritumoural conditions on expression pattern of SNCG in endometrial cancer (EC) in vitro. Compared to breast cancer cell lines, mRNA expression levels of all known SNCG isoforms 1-4 are significantly red ...[more]