Ontology highlight
ABSTRACT:
SUBMITTER: Sarkisyan KS
PROVIDER: S-EPMC4683004 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
PloS one 20151217 12
Genetically encoded photosensitizers, proteins that produce reactive oxygen species when illuminated with visible light, are increasingly used as optogenetic tools. Their applications range from ablation of specific cell populations to precise optical inactivation of cellular proteins. Here, we report an orange mutant of red fluorescent protein KillerRed that becomes toxic when illuminated with blue or green light. This new protein, KillerOrange, carries a tryptophan-based chromophore that is no ...[more]