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A Compact DNA Cube with Side Length 10 nm.

ABSTRACT: A small and compact DNA cube with zeptoliter volume is constructed by means of a generalized DNA brick concept using short synthetic oligonucleotides with varying lengths. By mimicking design principles from the DNA origami technique, the DNA cube offers higher stability and assembly yields compared to other approaches. Its potential application as nanoscale fluorescent probe is demonstrated using super-resolution imaging.

SUBMITTER: Scheible MB

PROVIDER: S-EPMC4707664 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature

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A Compact DNA Cube with Side Length 10 nm.

Scheible Max B MB Ong Luvena L LL Woehrstein Johannes B JB Jungmann Ralf R Yin Peng P Simmel Friedrich C FC

Small (Weinheim an der Bergstrasse, Germany) 20150821 39

A small and compact DNA cube with zeptoliter volume is constructed by means of a generalized DNA brick concept using short synthetic oligonucleotides with varying lengths. By mimicking design principles from the DNA origami technique, the DNA cube offers higher stability and assembly yields compared to other approaches. Its potential application as nanoscale fluorescent probe is demonstrated using super-resolution imaging. ...[more]

PMID: 26294348

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