Ontology highlight
ABSTRACT:
SUBMITTER: Liu O
PROVIDER: S-EPMC4712614 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
Liu Ou O Li Jiachen J Xin Yi Y Qin Yanwen Y Li Haiyang H Gong Ming M Liu Yuyong Y Wang Xiaolong X Li Jianrong J Zhang Hongjia H
BMC cardiovascular disorders 20160114
<h4>Background</h4>Thoracic aortic dissection (TAD) is the most common life-threatening disorder, and MMP-2 is involved in TAD pathogenesis. Our purpose is to systematically evaluate the association of the MMP-2 gene with TAD risk in Chinese Han population.<h4>Methods</h4>In our case-control study, we recruited 755 unrelated participants: 315 case participants with TAD and 440 controls. Twenty-two tag SNPs were selected from MMP-2 gene and were genotyped. Genotype data were analyzed by logistic ...[more]