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Crystal structure of 7-{[bis-(pyridin-2-ylmeth-yl)amino]-meth-yl}-5-chloro-quinolin-8-ol.

ABSTRACT: In the title compound, C22H19ClN4O, the quinolinol moiety is almost planar [r.m.s. deviation = 0.012?Å]. There is an intra-molecular O-H?N hydrogen bond involving the hy-droxy group and a pyridine N atom forming an S(9) ring motif. The dihedral angles between the planes of the quinolinol moiety and the pyridine rings are 44.15?(9) and 36.85?(9)°. In the crystal, mol-ecules are linked via C-H?O hydrogen bonds forming inversion dimers with an R 4 (4)(10) ring motif. The dimers are linked by C-H?N hydrogen bonds, forming ribbons along [01-1]. The ribbons are linked by C-H?? and ?-? inter-actions [inter-centroid distance = 3.7109?(11)?Å], forming layers parallel to (01-1).

SUBMITTER: Kubono K

PROVIDER: S-EPMC4719835 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature

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Crystal structure of 7-{[bis-(pyridin-2-ylmeth-yl)amino]-meth-yl}-5-chloro-quinolin-8-ol.

Kubono Koji K Kado Kimiko K Kashiwagi Yukiyasu Y Tani Keita K Yokoi Kunihiko K

Acta crystallographica. Section E, Crystallographic communications 20151128 Pt 12

In the title compound, C22H19ClN4O, the quinolinol moiety is almost planar [r.m.s. deviation = 0.012 Å]. There is an intra-molecular O-H⋯N hydrogen bond involving the hy-droxy group and a pyridine N atom forming an S(9) ring motif. The dihedral angles between the planes of the quinolinol moiety and the pyridine rings are 44.15 (9) and 36.85 (9)°. In the crystal, mol-ecules are linked via C-H⋯O hydrogen bonds forming inversion dimers with an R 4 (4)(10) ring motif. The dimers are linked by C-H⋯N ...[more]

PMID: 26870426

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2-({[(Pyridin-1-ium-2-ylmeth-yl)carbamo-yl]form-amido}-meth-yl)pyridin-1-ium bis-(3,5-di-carb-oxy-benzoate): crystal structure and Hirshfeld surface analysis.

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