Ontology highlight
ABSTRACT:
SUBMITTER: Potts RA
PROVIDER: S-EPMC4724463 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
Potts Rashaun A RA Tiffany Caitlin M CM Pakpour Nazzy N Lokken Kristen L KL Tiffany Connor R CR Cheung Kong K Tsolis Renée M RM Luckhart Shirley S
Immunobiology 20151125 3
Co-infections with malaria and non-typhoidal Salmonella serotypes (NTS) can present as life-threatening bacteremia, in contrast to self-resolving NTS diarrhea in healthy individuals. In previous work with our mouse model of malaria/NTS co-infection, we showed increased gut mastocytosis and increased ileal and plasma histamine levels that were temporally associated with increased gut permeability and bacterial translocation. Here, we report that gut mastocytosis and elevated plasma histamine are ...[more]