Colonic Fermentation Promotes Decompression sickness in Rats.
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ABSTRACT:
SUBMITTER: de Maistre S
PROVIDER: S-EPMC4745042 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Publications
Colonic Fermentation Promotes Decompression sickness in Rats.
de Maistre Sébastien S Vallée Nicolas N Gempp Emmanuel E Lambrechts Kate K Louge Pierre P Duchamp Claude C Blatteau Jean-Eric JE
Scientific reports 20160208
Massive bubble formation after diving can lead to decompression sickness (DCS). During dives with hydrogen as a diluent for oxygen, decreasing the body's H2 burden by inoculating hydrogen-metabolizing microbes into the gut reduces the risk of DCS. So we set out to investigate if colonic fermentation leading to endogenous hydrogen production promotes DCS in fasting rats. Four hours before an experimental dive, 93 fasting rats were force-fed, half of them with mannitol and the other half with wate ...[more]
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