Ontology highlight
ABSTRACT:
SUBMITTER: Valencia-Exposito A
PROVIDER: S-EPMC4759631 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Valencia-Expósito Andrea A Grosheva Inna I Míguez David G DG González-Reyes Acaimo A Martín-Bermudo María D MD
Nature communications 20160218
Contractile actomyosin networks generate forces that drive tissue morphogenesis. Actomyosin contractility is controlled primarily by reversible phosphorylation of the myosin-II regulatory light chain through the action of myosin kinases and phosphatases. While the role of myosin light-chain kinase in regulating contractility during morphogenesis has been largely characterized, there is surprisingly little information on myosin light-chain phosphatase (MLCP) function in this context. Here, we use ...[more]