Ontology highlight
ABSTRACT:
SUBMITTER: Kelley CA
PROVIDER: S-EPMC6232974 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Kelley Charlotte A CA Wirshing Alison C E ACE Zaidel-Bar Ronen R Cram Erin J EJ
Molecular biology of the cell 20180405 16
We identify the Caenorhabditis elegans myosin light-chain kinase, MLCK-1, required for contraction of spermathecae. During contraction, MLCK-1 moves from the apical cell boundaries to the basal actomyosin bundles, where it stabilizes myosin downstream of calcium signaling. MLCK and ROCK act in distinct subsets of cells to coordinate the timing of contraction. ...[more]