Ontology highlight
ABSTRACT:
SUBMITTER: He J
PROVIDER: S-EPMC4771093 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
He Jinshui J Fang Yanling Y Lin Xinfu X Zhou Huowang H Zhu Shaobo S Zhang Yugui Y Yang Huicong H Ye Xiaoling X
Medical science monitor : international medical journal of experimental and clinical research 20160226
BACKGROUND Growth hormone deficiency (GHD) is a major cause of congenital short stature. GHD patients have significantly decreased serum leptin levels, which are regulated by gene polymorphism of leptin and leptin receptor. This study thus investigated the relationship between gene polymorphism and susceptibility to GHD. MATERIAL AND METHODS A case-control study was performed using 180 GHD children in addition to 160 healthy controls. After the extraction of whole genomic DNA, the genotypes of l ...[more]