Ontology highlight
ABSTRACT:
SUBMITTER: Lavoie TN
PROVIDER: S-EPMC4778602 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
Lavoie Tegan N TN Carcamo Wendy C WC Wanchoo Arun A Sharma Ashok A Gulec Afife A Berg Kathleen M KM Stewart Carol M CM Nguyen Cuong Q CQ
Genomics data 20151122
TH17 cells and their associated signature cytokines, IL-17 and IL-22, are highly elevated in primary Sjögren's syndrome (pSjS). The levels of IL-22 present in sera showed significant correlations with many disease parameters, specifically hyposalivation, anti-SSB, anti-SSA/SSB, hypergammaglobulinemia and rheumatoid factor. The present study aims to examine the biological function of IL-22 on human salivary glands. To accomplish the goal, microarray analysis using the HumanHT-12 v4 Expression Bea ...[more]