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Cancer prevention in HIV-infected populations.


ABSTRACT: People living with human immunodeficiency virus (HIV) are living longer since the advent of effective combined antiretroviral therapy (cART). While cART substantially decreases the risk of developing some cancers, HIV-infected individuals remain at high risk for Kaposi sarcoma, lymphoma, and several solid tumors. Currently HIV-infected patients represent an aging group, and malignancies have become a leading cause of morbidity and mortality. Tailored cancer-prevention strategies are needed for this population. In this review we describe the etiologic agents and pathogenesis of common malignancies in the setting of HIV, as well as current evidence for cancer prevention strategies and screening programs.

SUBMITTER: Goncalves PH 

PROVIDER: S-EPMC4789150 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature

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Cancer prevention in HIV-infected populations.

Goncalves Priscila H PH   Montezuma-Rusca Jairo M JM   Yarchoan Robert R   Uldrick Thomas S TS  

Seminars in oncology 20150908 1


People living with human immunodeficiency virus (HIV) are living longer since the advent of effective combined antiretroviral therapy (cART). While cART substantially decreases the risk of developing some cancers, HIV-infected individuals remain at high risk for Kaposi sarcoma, lymphoma, and several solid tumors. Currently HIV-infected patients represent an aging group, and malignancies have become a leading cause of morbidity and mortality. Tailored cancer-prevention strategies are needed for t  ...[more]

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