Ontology highlight
ABSTRACT:
SUBMITTER: Kessler SN
PROVIDER: S-EPMC4797716 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
Angewandte Chemie (International ed. in English) 20160217 11
Presented herein is a mild, facile, and efficient iron-catalyzed synthesis of substituted allenes from propargyl carboxylates and Grignard reagents. Only 1-5 mol % of the inexpensive and environmentally benign [Fe(acac)3 ] at -20 °C was sufficient to afford a broad range of substituted allenes in excellent yields. The method tolerates a variety of functional groups. ...[more]