Cannabis use in early adolescence: Evidence of amygdala hypersensitivity to signals of threat.
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ABSTRACT:
SUBMITTER: Spechler PA
PROVIDER: S-EPMC4801124 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
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Cannabis use in early adolescence: Evidence of amygdala hypersensitivity to signals of threat.
Spechler Philip A PA Orr Catherine A CA Chaarani Bader B Kan Kees-Jan KJ Mackey Scott S Morton Aaron A Snowe Mitchell P MP Hudson Kelsey E KE Althoff Robert R RR Higgins Stephen T ST Cattrell Anna A Flor Herta H Nees Frauke F Banaschewski Tobias T Bokde Arun L W ALW Whelan Robert R Büchel Christian C Bromberg Uli U Conrod Patricia P Frouin Vincent V Papadopoulos Dimitri D Gallinat Jurgen J Heinz Andreas A Walter Henrik H Ittermann Bernd B Gowland Penny P Paus Tomáš T Poustka Luise L Martinot Jean-Luc JL Artiges Eric E Smolka Michael N MN Schumann Gunter G Garavan Hugh H
Developmental cognitive neuroscience 20150828
Cannabis use in adolescence may be characterized by differences in the neural basis of affective processing. In this study, we used an fMRI affective face processing task to compare a large group (n=70) of 14-year olds with a history of cannabis use to a group (n=70) of never-using controls matched on numerous characteristics including IQ, SES, alcohol and cigarette use. The task contained short movies displaying angry and neutral faces. Results indicated that cannabis users had greater reactivi ...[more]
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